Biological Safety

The purpose of the University's Biological Safety Program is to assist all Principal Investigators and research staff to safely handle biological agents in the laboratory. The proper Biological Risk Assessment form must be completed with every agent present in the laboratory or facility by analyzing the agent’s specific risk factors.

It is the responsibility of the Principal Investigator to assign the biosafety level to the agent(s) he/she uses in the laboratory, to implement the necessary practices and to design the laboratory according to the requirements of the specific biosafety level:

  • Biosafety Level 1 (BSL1)
  • Biosafety Level 2 (BSL2)
  • Biosafety Level 3 (BSL3)
  • Biosafety Level 4 (BSL4)

For more detailed and in depth information on the proper risk assessment process with biological agents and the classification in biosafety levels, check the CDC/NIH - Bopsafety in Microbiological and Biomedical Laboratories (BMBL), 4th Edition.


RESEARCH WITH ANIMALS

When working in research with animals, the risk assessment process must have in consideration the animal behavior and physiology as a key risk factor. This additional factor conveys the need to classify research with animals and infectious agents into a animal biosafety level. It is the responsibility of the Principal Investigator to assign the animal biosafety level:

  • Animal Biosafety Level 1 (ABSL1)
  • Animal Biosafety Level 2 (ABSL2)
  • Animal Biosafety Level 3 (ABSL3)
  • Animal Biosafety Level 4 (ABSL4)

The requirements to obtain privileges for the use of animals for research purposes are under the responsibility of the Institutional Animal Care and Use Committee (IACUC). For more detail information login at the IACUC website or by calling (305) 243-2311.

For more detailed and in depth information on the proper risk assessment process with animal biological agents and the classification in biosafety levels, check the CDC/NIH - Bopsafety in Microbiological and Biomedical Laboratories (BMBL), 4th Edition.


RECOMBINANT DNA RESEARCH

Compliance with the NIH Guidelines requires the Principal Investigators who are working with Recombinant DNA (rDNA) to make the appropriate biological risk assessment and to assign the appropriate risk group as per the NIH guidelines:

  • Risk Group 1 (RG1)
  • Risk Group 2 (RG2)
  • Risk Group 3 (RG3)
  • Risk Group 4 (RG4)

To get approval to do rDNA research at the University of Miami, you must contact the Institutional Biosafety Committee (IBC) by login in at: http://www.miami.edu/rdna or by calling at (305) 243-9291.

For more detailed and in depth information on the proper risk assessment process with rDNA biosafety level and the classification in biosafety levels, check the CDC/NIH - Bopsafety in Microbiological and Biomedical Laboratories (BMBL), 4th Edition.

For more information on the biological safety program at the University of Miami or on any issues with biological agents, please contact us.